Our research
Environment
1. Supporting the transition to an environment free from toxic substances
Success Story #1
Anticipating the harmful effects of chemicals without resorting to animal testing
Predicting the impact of chemicals on our health without resorting to animal testing; this is the ambition of Invitrolize, a LIST spin-off founded in June 2022 and registered with the Luxembourg Chamber of Commerce. The company markets innovative 3D in vitro alveolar models to predict the risks of respiratory sensitisation and irritation. For the first time, these models can be used to predict respiratory sensitisation in realistic exposure conditions.The spin-off is based in a laboratory in the Belvaux building and is developing its activities in the form of a start-up with the aim of sustainably improving assessments of the toxicity of chemicals and their impact on health.
On the 2nd national 3R day, the National League for the Protection of Animals (Lëtzebuerger Déiereschutzliga) also received an award for the contribution made by LIST and its Environmental Health team to reduce, replace or significantly perfect the use of animals in research, thanks to the development of these in vitro tests on human respiratory tracts.
Contact: Arno Gutleb
More information: Invitrolize
Success Story #2
Working towards a better assessment of chemicals for the benefit of human health and the environment
Since 2022, LIST has held the Luxembourg seat on the Socio-economic Analysis Committee (SEAC) of the European Chemicals Agency (ECHA). Appointed by the Ministry of the Economy, Oona Freudenthal contributes to the work of SEAC, whose role is to assess the socio-economic impact of potential legislative measures with regard to chemicals, whether concerning proposals to restrict manufacturing, marketing or use of a substance, or the availability, appropriateness and technical feasibility of alternatives to using such hazardous substances.
In collaboration with the IT for Innovative Services department and with a view to an artificial intelligence (AI) app, Oona also began research in 2022 within the framework of a private-public partnership funded by the AXA Foundation. Her research project aims to help authorities and policy makers to establish an appropriate regulatory framework for these substances and to better manage the risks they pose to human health and the environment. The results of this research project will provide a better understanding of the risks chemicals pose to industrial clients, public health and citizens. This combination of an applied research project and a mission to implement a science-based policy strengthens LIST's activities and the offer of political support in the field of security and sustainability through design (safe and sustainable by design).
Contact: Oona Freudenthal
Success Story #3
TranszeroWaste, improving the reuse of waste as a raw material
Europe's dependence on imported steel sources is increasing and is jeopardising goals for the decarbonisation of industry. In order to guarantee the independence of this sector as well as its compatibility with decarbonisation objectives, we are pursuing, together with our European partners, an ambitious objective to optimise the recycling of residues throughout the steel production chain, from both a techno-economic and environmental perspective.
The Horizon Europe TranszeroWaste Project, coordinated by LIST, aims to improve the reuse of waste as a raw material in two promising processes to decarbonise the sector, using hydrogen and electricity. LIST goes beyond assessing the technical and economic performance of these new recycling technologies and takes into account their eco-design and their environmental assessment in order to ensure more sustainable choices. In the long term, these innovative solutions will pave the way for a steel production chain that will not only depend less on imports, but will also be more circular and more environmentally friendly.
Contact: Elorri Igos
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2. Biotechnology for sustainable growth and development
Success Story #1
Taking a green step on the red planet
According to the international roadmap for space exploration, the first human installations on the planet Mars are planned by 2040. The cultivation of edible plants in situ on Martian or lunar surfaces will generate oxygen while at the same time producing food for visitors and future colonies. Water emitted and purified by plants will be able to be condensed and recycled. In line with the national research and innovation strategy and its objectives focusing on space resources to support life, LIST has begun to study plant growth on the simulated Martian regolith using a combination of imaging and omics. Italian ray-grass was used as a model of a rapidly growing herbaceous species.
The research teams showed that plants can grow on simulated regolith, despite the scarcity of the fundamental element nitrogen. They can even regrow after being cut. The ray-grass can therefore be used in a hypothetical scenario where it is harvested to obtain the organic matter to be used as feed. The molecular data obtained for the first time showed changes in the plant mechanism, whereby the leaves and roots adapted to grow in the substrate. The results published in the Science of the Total Environment attracted the interest of NASA's Open Science Data Repository (GeneLab) and were highlighted in the Mascot newsletter.
Contact: Gea Guerriero
Success Story #2
Wastewater treatment with a biological granular treatment process
Aerobic granular sludge is now an alternative to the conventional process of activated sludge in biological wastewater treatment. Wastewater treatment plants equipped with aerobic granular sludge achieve high processing efficiency and have lower investment and operating costs than plants equipped with conventional activated sludge, which are in the majority in Luxembourg.
LIST has developed a model for aerobic granular sludge intended for engineering applications based on mathematical process models. This model can predict the concentrations of pollutants during the different operational phases of treatment.
In line with the digitisation objectives of the national research and innovation strategy, LIST studied the mechanical modelling of biological wastewater treatment processes and its application to a pilot unit at a local operator's premises. The scientific and technical aspects of this work were published in the Journal of Chemical Technology and Biotechnology (Society for Chemical Industry, London, UK), where the authors also presented a perspective article on the general use of the Monod kinetic model.
Contact: Mario Plattes
Success Story #3
Improving the monitoring of risks related to cyanobacteria in Luxembourg's bathing waters
For more than 10 years, LIST has been commissioned by the Water Management Authority to carry out the operational monitoring of the proliferation of cyanobacteria – blue algae – in official bathing waters in accordance with a European directive. These algae can release toxins and pose a threat to public health.
Throughout the world, cyanobacteria are causing problems in freshwater ecosystems. According to current climate change projections, the problem is expected to get worse. In order to protect public health, it is essential to gain a better understanding of these cyanobacteria and, in particular, their life cycle in order to propose management strategies. In this regard, LIST provides data that can trigger alerts or the closure of Luxembourg's beaches for a period of time.
In 2022, LIST carried out three projects involving the deployment and testing of a unique combination of cutting-edge technologies. In particular, this combination brings together remote detection and in situ detection, automated image acquisition and the rapid dosage of cyanotoxins in order to stimulate the collection of data in the field and to provide information on the risks associated with effective spatial and temporal resolution. An early warning system has been developed for the effective protection of public health, while at the same time improving our understanding of cyanobacteria in order to better forecast algal blooms. A participatory monitoring project has recently been launched, involving citizens in the reporting and documentation of algal blooms in waters used for recreational purposes.
Contact: Jean-Baptiste Burnet
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3. Detecting the effects of climate change for better risk management
Success Story #1
Remote detection of the Earth's evapotranspiration for NASA and ESA
The Ecosystem Spaceborne Thermal Radiometer Experiment on the Space Station (ECOSTRESS) monitors water loss due to evaporation and transpiration processes on the Earth's surface. LIST contributed to this mission by successfully implementing the European ECOSTRESS hub and supplying lots of ecosystem data on the thematic operating platform on food security.
This achievement led to the EURANUS follow-up project, funded by the European Space Agency (ESA), which, on a European and African scale, aims to develop products relating to the surface temperature of the land, evaporation, productivity of ecosystems and the efficiency of water use, using all ECOSTRESS archives.
Thanks to this effort, LIST's "Surface Temperature Initiated Closure" (STIC) evaporation model has become one of the NASA Jet Propulsion Laboratory's official algorithms for generating ECOSTRESS products on the water cycle on a continental scale. These evaporation products with high spatial resolution from the International Space Station's sensor greatly facilitate future studies attempting to quantify the impact of ecosystem restoration on water availability at a regional level, as already reported in Nature Geosciences by the former PhD student from DTU Hydro-CSI, Anne Hoek van Dijke, and her supervisors.
Contact: Kaniska Mallick
Success Story #2
Developing new knowledge and sustainable solutions to combat diseases and agricultural pests
At the end of 2022, a new Biosafety Level 3 laboratory was set up and officially opened at LIST's Belvaux site. Vector-borne plant pathogens affect almost all crops and can lead to significant economic losses for farmers. A laboratory of this kind is therefore able to carry out experiments on plant pathogens and pests that are not yet present in our region but which could become established in the future due to climate change. These research topics are currently being studied at LIST as part of the Horizon 2020 Virtigation project.
Our new laboratory therefore represents a valuable asset for generating new knowledge and sustainable solutions concerning agricultural pests in a changing environment. The next stage will be to test new biopesticides in the laboratory. These biopesticides to combat parasites and quarantine diseases are being developed in collaboration with the Green Tech Innovation Centre.
Contact: Matteo Ripamonti
Success Story #3
Better forest management in the face of global change
As part of the FNR Mobility project "Tracing rainfall through forest canopies into catchments" (TRAFIC), Professor Richard Keim (Louisiana State University) joined forces with LIST in 2022 in view of their common research interests, namely the response of forests to global change.
The main TRAFIC objective was to understand the mechanisms involved in conveying water through forest canopies into catchments. An initial tracker-assisted attempt (with stable isotopes of oxygen and hydrogen) to measure water flow routes and residence times in a forest canopy-soil linked continuum was carried out, in a pioneering way, in forests around the city of Luxembourg.
TRAFIC has provided new data and a process-driven understanding that will ultimately improve our ability to predict changes in how forests respond to climate change and to adapt forest management strategies accordingly.
Contact: Stan Schymanski
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4. Developing smart systems for a clean energy transition
Success Story #1
Making e-mobility in the electricity network a reality
Luxembourg is increasingly dependent on renewable energy sources, which fluctuate more than traditional sources. The country is also facing other forms of consumption due to the decarbonisation of the heating and transport sectors. In fact, it is essential for its electricity network.
Encevo, a leading player in the field of sustainable energy in Luxembourg and the Greater Region, has signed a framework partnership agreement with LIST and the Interdisciplinary Centre for Security, Reliability and Trust (SnT) of the University of Luxembourg with the aim of uniting their innovative forces in order to speed up the transition to a sustainable energy landscape. The first project resulting from this partnership, entitled "Flexibility possibilities and user behaviour analysis" (FlexBeAn), focuses on smart networks.
In this partnership, LIST focuses on the areas of society and network flexibility. The objective is to implement an integrated model capable of assessing the flexibility of different sectors (households, industries, SMEs and in the field of e-mobility) in order to enable users to adapt their consumption in line with the overall demand for electricity on the network in the long term.
Contact: Daniel Koster
More information: project page
Success Story #2
Using energy digitisation and artificial intelligence to ensure we adapt to renewable energies
The objective set by the European Union to be climate neutral by 2050 will have a profound effect on the energy sector, which will be increasingly reliant on distributed energy sources such as renewable energy sources, energy storage, electric vehicles and variable demands connected to distribution systems.
In the long term, operational planning decisions made by agents will no longer be sufficient to maintain the security and stability of distributed systems with increasingly variable operation. As a result, most decisions need to be made in situ and in real time based on the instantaneous data from the distributed networks.
In order to answer these questions, the new project "Learning Enabled Autonomous Real-Time Operation for Distribution Grids" (LEAP), funded by the National Research Fund (FNR), is providing innovative solutions based on cutting-edge technology such as machine learning, which is a key tool for carrying out the energy transition. The project will reveal new knowledge and methods in the fields of energy digitisation and artificial intelligence in order to ensure we adapt to the increasing use of renewable energies and the acceleration of the energy transition, with a view to long-term research.
Contact: Jun Cao
Success Story #3
Coordinating the Luxembourg pilot agriphotovoltaic farm with hydrogen storage and batteries
Demonstrating innovative forms of storage and successfully operating them and integrating them into energy systems and innovative network architectures is essential to making the transition to clean energy.
The Horizon Europe project "Innovative Energy Storage Technologies towards Increased Renewables Integration and Efficient Operation" (I-STENTORE) obtained by LIST in 2022 examines the integration of various energy storage solutions and their combinations. Innovative storage systems will be presented and their cooperation with integrated assets will be co-optimised, with the final objective being to achieve reliability, energy quality, profitable exploitation and to maximise asset life.
LIST is the technical coordinator of the project. It is managing a demonstrator in Luxembourg to study the availability, robustness and security of several energy production and storage systems on an agriphotovoltaic farm (Agri-PV). The aim is to optimise the use of locally produced renewable resources in order to meet the needs of the farm, while at the same time supporting the operator's overall network. Within the framework of this demonstration, LIST is collaborating, in particular, with the Luxembourg companies European Dynamics and Green Power Storage Solutions.
Contact: Pedro Rodriguez & Gregory Baltas
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